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Cancer Biology Research

Cancer Biology Research
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EXAMPLES OF FUNDED PROJECTS
        (1) Studies of the properties of the membranes of malignant cells; (2) studies of the molecular genetics of oncogenes and tumor suppressor genes and the proteins they encode; (3) studies of the mechanism of action of growth factors and other growth modifiers and differentiation agents; (4) studies of the regulation of the biology of tumor cells by their micro environment; (5) studies of the synthesis, structure, and function of humoral factors that participate in, activate, and/or regulate the immune response to tumors, including interferons, interleukins, growth factors, helper factors, suppressor factors, etc., as they are involved in immune responses to tumors; (6) studies of the immunobiology of lymphocytes, macrophages, and other cells that may participate in immune surveillance responses (e.g., natural killer cells and cytotoxic T cells); (7) studies of the immune mechanisms involved in effective immunotherapy in animal models and humans, including studies on the development vaccine approaches to cancer therapy or prevention; (8) studies of bone marrow transplantation in humans and animals as a treatment for cancer when the emphasis is on immunologic problems such as immune reconstitution, sensitization and graft-versus-host disease.

PROGRAM ACCOMPLISHMENTS
        Competing FY 2005 RPG act. 358 awards, which were 21.1% of applications received. Competing FY 2005 SBIR/STTR act. 20 awards, which were 18.2% of applications received. Fiscal year 2006 est 1,668 total awards and FY 2007 est 1,605 total awards.

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