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National Center for Research Resources


National Center for Research Resources

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EXAMPLES OF FUNDED PROJECTS
        BT: Supported research projects, biomedical technology resources, and exploratory grants that develop and disseminate complex techniques and equipment to the biomedical research community Examples include: (1) The analysis using synchrotron X-rays of the crystal structure of the myosin head that is the key to the contraction of muscle; (2) development of a two-photon laser method to directly explore chemical processes in living cells; and (3) use of a computer network and a super computer to remotely operate an electron microscope in real time and analyze the image. SIG: Types of instruments supported include but are not limited to: electron microscopes, NMR spectrometers, mass spectrometers, DNA sequencers, image analyzers, and computer graphics systems. CR: A typical center supports multiple projects from many disciplines, such as internal medicine, pediatrics, surgery, and obstetrics and gynecology. Projects may relate to all aspects of disease mechanisms and may include projects in nutrition, diabetes, growth and development, genetics, immunology, AIDS and other areas. SEPA: (1) improving the scientific knowledge base of current and prospective precollege teachers and teachers' instructional skills can be enhanced. (2) developing innovative materials, techniques, and/or curricula where there is a demonstrated lack of suitable materials and a need for scientific advice. (3) organizing and conducting programs to provide for laboratory experiences in the biological sciences for students from kindergarten through twelfth grade levels. (4) preparation and/or presentation of materials for biomedical/behavioral science education or for a media program on science. CM: Eight National Primate Research Centers are supported to provide special environments in models. They maintain colonies of over 18,000 animals, representing 32 species of nonhuman primates, for research and breeding purposes. Projects for the characterization and development of animal models were supported, but were limited to those that displayed potential for multi-categorical utilization. Projects that attempt to establish an animal model for a specific disease should be directed to the Institute/Center of NIH that supports categorical research in that area. The etiology and control of important naturally-occurring laboratory animal diseases have been studied. Biological Models and Materials Research Resource centers were supported to provide a large variety of materials to the research community. These centers acquire, authenticate, maintain, and distribute biomaterials to both basic researchers and clinical investigators. For example, resources distribute invertebrates such as squid, mollusks, and nematodes), cultures of microorganisms, cell lines, fungi, yeast, hybridomas, cloned genes, DNA probes and libraries, and recombinant DNA and oncogenes. Also supported is a project to collect data on the genes and metabolism of the bacterium Escherichia coli and to encode this information in a computer database that allows investigators to access genetic metabolic data in a graphic, user-friendly manner. RI: RCMI: (1) Research Center for Gene Structure and Function; (2) Cellular and Molecular Basis of Development Research Center; (3) Neuroscience Center; and (4) Research Infrastructure for Scientific Excellence. RCRII: Research Infrastructure for Clinical and Collaborative Research. IDeA: Human Genetics Research Enhancement. RFIP: Developing and Improving Institutional Animal Resources. Institutional animal resource improvement projects were supported to assist institutions in upgrading and developing centralized animal resource programs.

PROGRAM ACCOMPLISHMENTS
        In fiscal year 2005, there were 117 Research Project Grants; in FY 2006, it is estimated that there will be 119 and in FY 2007 114. There were 103 Clinical Research Resource Center awards in FY 2005. It is estimated that there will be 105 in FY 2006 and 101 in FY 2007. There were 51 Biomedical Technology Resource Centers in FY 2005 and it's estimated there will be 51 in FY 2006 and 50 in FY 2007. There were 94 Special Comprehensive Centers in FY 2005 and it is estimated that there will be 95 in FY 2006 and 93 in FY 2007. There were 51 Comparative Medicine Centers in FY 2005. It is estimated that there will be the same number in FY 2006 and 50 in FY 2007. There were 17 Research Centers in Minority Institutions in FY 2005 and it is estimated that there will be the same number in FY 2006 and FY 2007. There were 535 Other Research Grants in FY 2005. It is estimated that there will be 508 in FY 2006 and 511 in FY 2007. There were 134 Full Time Training Positions in FY 2005. It's estimated that there will be 132 in FY 2006 and FY 2007. There were 69 Research and Development Contracts in FY 2005. It is estimated that there will be 73 in FY 2006 and 72 in FY 2007. There were 17 Construction Grants in FY 2005.

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