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Research and Training in Complementary and Alternative Medicine


Research and Training in Complementary and Alternative Medicine

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EXAMPLES OF FUNDED PROJECTS
        The Centers program is supporting a variety of on-going studies including the use of Mindfulness-Based Stress Reduction, a meditative approach, to help reduce stress and better manage emotions, in people with early stage HIV. Specifically, the effects of meditation on the immune system will be studied to see if meditation can help slow disease progression and delay the need for antiretroviral treatment. Center investigators will evaluate whether certain traditional Chinese medicines and an electrical acupuncture technique can be used to prevent addiction relapse and craving for alcohol and drugs of abuse. They will also seek to determine the physiological mechanisms by which these Chinese medical treatments affect addictive behavior. Several centers will be exploring the mechanisms of action of acupuncture using both animal models and human studies employing state-of-the-art real-time imaging technology. Other studies will examine the potential use of antioxidant CAM therapies for asthma. Researchers will investigate whether these antioxidant treatments can minimize airway inflammation in response to common triggers of asthma, such as ozone or inhaled allergens. Also explored will be the use of mushroom extracts to enhance the immune system's response to tumors, and the healing power of "placebo" particularly strategies to maximize placebo's benefits, improve clinical trial design, and gain insight into mechanisms underlying mind-body medicine. Finally, center investigators will study the effects of osteopathic manipulation on the musculoskeletal system, lymphatic fluid flow, and reduction of pain from back and neck strain.

PROGRAM ACCOMPLISHMENTS
        In fiscal year 2005, 317 total grants were funded. It is estimated that 293 grants will be funded in fiscal year 2006 and 290 grants in fiscal year 2007. In fiscal year 2005, 6 centers were funded using the Specialized Centers (P01) mechanism. Topics for these centers include acupuncture, asthma, botanicals, cancer, cardiovascular disease, HIV/AIDS and substance abuse. Currently, five developmental centers are supported that incorporate close collaborations between CAM and conventional institutions. One of these developmental centers is at a school of osteopathic medicine, one at a school of chiropratic medicine, and one at a school of traditional chinese medicine (e.g., acupuncture). In addition, developmental centersare funded on mind/body medicine. Several large clinical trials were in progress including: Hypericum for Minor Depression; Ginkgo biloba for Preventing Dementia; Shark Cartilage as an adjunctive therapy for non-small Cell Lung Cancer; Saw Palmento for benign prostatic hyperplasgia; EDTA Chelation therapy for Coronary Artery Disease. Numerous investigator-initiated research grants were studying the breath of CAM modalities including clinical and basic studies of acupuncture, botanicals, chiropractic, homeopathy, massage therapy, naturopathy, and Reiki to name a few. Finally, in FY 2005, 17 individual postdoctoral and predoctoral fellows and 9 institutional training awards were funded under National Research Service Awards (NRSA).

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Research and Training in Complementary and Alternative Medicine


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Research and Training in Complementary and Alternative Medicine



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