| EXAMPLES OF FUNDED PROJECTS |
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EXAMPLES OF FUNDED PROJECTS: The Superfund Basic Research Program is university-based basic research and training program consisting of coordinated, multi-component interdisciplinary programs that link basic biomedical research with related engineering, hydrogenological epidemiological, and ecological studies. This interdisciplinary program supports basic research in the following: (1) Development and use of methods and technologies to detect hazardous substances in the environment such as the development of a cell bioassay system that detects dioxin-like HAHs and PAHs in extracts of biological, environmental, and food and feed samples; (2) development of advanced techniques for the detection, assessment, and evaluation of the effects of human health of hazardous substances such as a number of projects focused on arsenic detection, biomarker development, mechanisms of action and remediation methods; (3) development of methods to assess the risk to human health presented by hazardous substances such as the projects focused on the human health effects associated with exposure to PCBs ; and (4) the development and use of basic biological, chemical, and physical methods and technologies to reduce the amount of toxicity of hazardous substance such as the development of bioremediation strategies using microbes and other organisms to reduce organics and metals from environmental media. |
| PROGRAM ACCOMPLISHMENTS |
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During fiscal year 2005, the Superfund Basic Research Program made 15 supplemental awards to grantees supporting multi-disciplinary approaches in advancing the understanding of human health effects of environmental exposures to hazardous substances and in developing innovative technologies for remediating these contaminants. It is expected that nine noncompeting awards will be issued in FY2006. In addition, a Request for Applications released in September 2003 to allow for the recompetition of this multi-disciplinary research program resulted in the awarding of nine grants in fiscal year FY 2005. It is expected that an additional six to seven competing awards will be made in FY2006 from this solicitation. It is also expected that 15 to 16 noncompeting awards will be issued in FY2007. Research included developing tools for monitoring the effects of endocrine-disrupting environmental chemicals; determining that there is a significant relationship between smoking status, cumulative arsenic exposure, and increased risk of bladder cancer; pioneering the use of a powerful new method of studying the biogeochemical behavior of contaminants in sediments; using molecular modeling techniques to study and design chemically diverse materials for the sorption and detoxification of hazardous compounds; and developing fish models that could act as biosensors for Superfund chemical interactions which would allow for continuous qualitative examination of developmental effects. Also, during fiscal year 2005, the Superfund Basic Research Program made one competing Phase 1 and three noncompeting Phase 2 Small Business Innovative Research awards in the general area of hazardous waste remediation and monitoring. It is expected that at least one competing Small Business Innovative Research award will be made in fiscal year 2006 and FY2007. |
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NIEHS Superfund Hazardous Substances_Basic Research and Education
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NIEHS Superfund Hazardous Substances_Basic Research and Education
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