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Oral Diseases and Disorders Research


Oral Diseases and Disorders Research

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EXAMPLES OF FUNDED PROJECTS
        (1) Research center support coordinated studies of periodontal diseases, clinical cores, dental caries, oral biology, craniofacial disorders, oral cancer, minority oral health, and materials sciences; (2) genomic sequencing of bacterial oral pathogens; (3) metalloproteinases in developing enamel; (4) genetic basis of ectodermal dysplasia; (5) biofilms, including studies of microbial ecology, physiology and transmission; (6) prevention and control of infectious diseases including behavioral approaches, antibiotics and vaccines; (7) development of anti-streptococcal antibodies in genetically engineered plants; (8) endodontic treatment and management of oral AIDS-Kaposi's sarcoma for HIV positive patients; (9); development of HIV diagnostic assays utilizing saliva; (10) epidemiology of HIV associated opportunistic oral infections; (11) papilloma viruses in oral cancer; (12) regulated expression of extra-cellular matrix proteins in oral cancer; (13) biobehavioral aspects of temporomandibular disorders (TMD); 14)pharmacological management of TMDs; (15) brainstem mechanisms controlling jaw movement; (16) neural control of swallowing and mastication; (17) construction of chimeric salivary molecules; (18) etiology and pathology of Sjogren's syndrome; (19) guided bone regeneration with morphogenic protein; and (20) computer assisted detection of dental caries.

PROGRAM ACCOMPLISHMENTS
        In fiscal year 2005, 735 new and competing research project grant applications were received; 179 were awarded at a cost of $57,367,000. The Institute also supported 488 noncompeting research project grants at $177,170,000; 39 SBIR/STTR awards at $8,375,000; 7 research centers at $12,260,000; 90 grants in the career development award program at $12,939,000, 37 other research grants at $12,937,000, and 362 positions in the NRSA program at $15,908,000. In fiscal year 2006, the NIDCR expects to support 481 noncompeting research project grants at $175,030,126,000, 177 competing grants at $56,873,000, 34 SBIR/STTR awards at $8,400,000, 7 research centers at $13,194,000, 87 grants in the career development awards program at $12,939,000, 37 other research grants at $11,905,000, and 340 positions in the NRSA program at $15,000,000. Funding for fiscal year 2007 is estimated as follows: 451 noncompeting research project grants at $171,443,000, 169 competing grants at $54,177,000, 34 SBIR/STTR awards at $8,330,000, 8 research centers at $15,259,000, 90 grants in the career development award program at $12,350,000, 27 other research grants at $12,275,000, and 337 positions in the NRSA program at $14,910,000.

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Oral Diseases and Disorders Research


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Oral Diseases and Disorders Research



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